What is Progesterone Cream? This topical HRT formulation contains bioidentical Progesterone at 100mg strength, designed for hormone replacement therapy research and clinical use. Supplied as a 90-day cream supply, it is formulated to study progesterone receptor activation, endometrial regulation, and transdermal progesterone delivery at a foundational dose under controlled clinical conditions.

Mechanism of Action Bioidentical Progesterone binds to progesterone receptors (PR-A and PR-B) within target tissues, activating intracellular signaling cascades that regulate endometrial health, neuroendocrine balance, and cellular homeostasis. At 100mg, transdermal delivery provides consistent systemic absorption, supporting steady progesterone plasma levels while modulating GABAergic pathways that influence sleep and mood regulation.

The Science

• Study progesterone receptor-ligand binding and intracellular signaling at baseline dose
• Evaluate transdermal progesterone absorption and systemic bioavailability
• Assess endometrial regulation and uterine protection mechanisms
• Analyze GABAergic and neuroendocrine modulation via progesterone activity
• Conduct reproducible low-dose progesterone in vitro and clinical studies

Purity & Quality

• ≥99% purity verified via HPLC
• Certificate of Analysis included

Storage: Store at room temperature in a cool, dry place

Intended Use This compound is intended strictly for use by trained professionals. Our compounds are not “research only” and require an Rx, which we provide through our tele-health and/or a HIPAA Compliant Intake Form reviewed by a Medical Professional.

Note BodyBossRx works with various top pharmacies to ensure you will always have your medication efficiently; therefore, labeling may differ.

Terms of Sale These are sterile compounds. All sales are final. If you are not a professional, the Purchaser (YOU) assumes full responsibility to be guided on dosing, administering, etc. by a medical professional.